131 Stressed out keratinocytes, new insights into psoriasis lesion formation
نویسندگان
چکیده
منابع مشابه
Induction of secondary axis in hydra revisited: New insights into pattern formation
In 1909, several years before the famous `Organizer’ experiments of Spemann and Mangold, Ethel Browne demonstrated induction of a secondary axis in hydra by grafting a hypostome. Based on this and subsequent work, in the late sixties, Lewis Wolpert proposed the theory of morphogen gradients and positional information. We have studied secondary axis induction by hypostome and foot tissue using t...
متن کاملinduction of secondary axis in hydra revisited: new insights into pattern formation
in 1909, several years before the famous `organizer’ experiments of spemann and mangold, ethel browne demonstrated induction of a secondary axis in hydra by grafting a hypostome. based on this and subsequent work, in the late sixties, lewis wolpert proposed the theory of morphogen gradients and positional information. we have studied secondary axis induction by hypostome and foot tissue using t...
متن کاملNew insights into zeolite formation from molecular modeling
We review recent molecular modeling efforts to shed light on the mechanisms of zeolite formation. We focus on studies that model the early stages of silica polymerization and zeolite nucleation. Electronic structure calculations, classical molecular dynamics, atomistic Monte Carlo simulations and Monte Carlo simulations of lattice models have been used to probe the formation of zeolites and mes...
متن کاملStressed out and asthmatic
On page 157, Sarmento and colleagues show how the developmental regulator protein Notch1 advances the cell cycle. Activation of Notch1 induced the production of a protein that chops up cell cycle inhibitors, leading to a shortened G1 phase and a faster transition into S phase (but no overall increase in proliferation). The Notch family of transmembrane receptors regulates both cell fate decisio...
متن کاملNew insights into PTEN.
The functions ascribed to PTEN have become more diverse since its discovery as a putative phosphatase mutated in many human tumors. Although it can dephosphorylate lipids and proteins, it also has functions independent of phosphatase activity in normal and pathological states. In addition, control of PTEN function is very complex. It is positively and negatively regulated at the transcriptional...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2017
ISSN: 0022-202X
DOI: 10.1016/j.jid.2017.07.441